amakuru

Umuvuduko ukabije wamaraso mugihe utwite urashobora gutera eclampsia no kuvuka imburagihe kandi nimpamvu nyamukuru itera uburwayi bwababyeyi nimpinja. Nkigipimo cyingenzi cyubuzima rusange, Ishami ry’ubuzima ku isi (OMS) rirasaba ko abagore batwite bafite inyongeramusaruro ya calcium idahagije yongerera mg 1000 kugeza 1500 mg ya calcium buri munsi. Ariko, kubera inyongera ya calcium igoye, ishyirwa mubikorwa ryiki cyifuzo ntabwo gishimishije.

Igeragezwa ryemewe ryakozwe mu Buhinde no muri Tanzaniya ryakozwe na Porofeseri Wafie Fawzi wo mu Ishuri Rikuru ry’Ubuzima rusange rya Harvard muri Amerika ryerekanye ko inyongera ya calcium nkeya mu gihe cyo gutwita itari mbi nko kwiyongera kwa calcium nyinshi mu kugabanya ibyago byo kwibasirwa na eclampsia. Mu rwego rwo kugabanya ibyago byo kubyara imburagihe, ibigeragezo byo mu Buhinde na Tanzaniya byagize ibisubizo bidahuye.

Ibigeragezo byombi byitabiriwe n'abantu 11,000 bafite imyaka 18, imyaka yo gutwita

Kuri preeclampsia, umubare w’abantu 500 mg na 1500 mg mu rubanza rw’Ubuhinde wari 3.0% na 3,6%, (RR, 0.84; 95% CI, 0.68 ~ 1.03); Mu rubanza rwa Tanzaniya, abanduye bari 3.0% na 2.7%, (RR, 1.10; 95% CI, 0.88 ~ 1.36). Ibigeragezo byombi byerekanaga ko ibyago bya preeclampsia bitari bibi mu itsinda rya mg 500 kuruta mu itsinda rya mg 1500.

Kubyara imburagihe, mubigeragezo byu Buhinde, ubwandu bwa mg 500 na groupe ya mg 1500 bwari 11.4% na 12.8%, (RR, 0.89; 95% CI, 0.80 ~ 0,98), ubudashyikirwa bwashyizweho mugaciro kangana na 1.54; Mu igeragezwa rya Tanzaniya, umubare w'abana bavutse batagejeje igihe wari 10.4% na 9.7%, (RR, 1.07; 95% CI, 0.95 ~ 1.21), warengeje agaciro kari munsi ya 1.16, kandi kutarenza urugero ntabwo byemejwe.

Mu mpande zombi ndetse n’umutekano, nta kimenyetso cyerekana ko itsinda rya mg 1500 ryarushaga 500 mg. Isesengura ryakozwe n’ibyavuye mu bigeragezo byombi ryasanze nta tandukaniro riri hagati y’amatsinda 500 mg na 1500 mg muri preeclampsia, ibyago byo kubyara imburagihe, hamwe n’ibisubizo by’umutekano ndetse n’umutekano.

Ubu bushakashatsi bwibanze ku kibazo cy’ubuzima rusange bw’inyongera ya calcium ku bagore batwite hagamijwe gukumira preeclampsia, kandi bukora igeragezwa rinini ryateganijwe mu bihugu byombi icyarimwe kugira ngo risubize ikibazo cy’ubuhanga ariko kidasobanutse neza ku bijyanye n’uburyo bwiza bwo kongeramo calcium. Ubushakashatsi bwari bufite igishushanyo mbonera, ubunini bw'icyitegererezo, icyerekezo cya kabiri-gihumye, hypothesis itari munsi, hamwe n’ibisubizo bibiri by’amavuriro bya preeclampsia no kuvuka imburagihe nkibisobanuro bibiri, byakurikiranye iminsi 42 nyuma yo kubyara. Muri icyo gihe, ireme ry’irangizwa ryari ryinshi, igipimo cy’igihombo cyo gukurikiranwa cyari gito cyane (99.5% byakurikiranwe ku byavuye mu gutwita, Ubuhinde, 97.7% Tanzaniya), kandi kubahiriza byari hejuru cyane: ijanisha ryo hagati ryubahirizwa ryari 97.7% (Ubuhinde, 93.2-99.2 intera intera intera interaire), 92.3% (Tanzaniya, 82.7-97.1).

Kalisiyumu nintungamubiri zikenewe mu mikurire y’inda no gukura, kandi icyifuzo cya calcium ku bagore batwite cyiyongera ugereranije n’abaturage muri rusange, cyane cyane mu gihe cyo gutwita igihe umwana akuze vuba kandi minerval igabanuka, hagomba kongerwamo calcium nyinshi. Kwiyongera kwa Kalisiyumu birashobora kandi kugabanya irekurwa rya hormone ya parathiyide hamwe na calcium yo mu nda ya calcium ku bagore batwite, kandi bikagabanya kugabanuka kw'imiyoboro y'amaraso n'imitsi yoroheje ya nyababyeyi. Igeragezwa ryagenzuwe na Placebo ryerekanye ko inyongera ya calcium nyinshi mu gihe cyo gutwita (> 1000 mg) yagabanije ibyago byo kwandura preeclampsia hejuru ya 50% naho ibyago byo kubyara imburagihe bikagabanukaho 24%, kandi kugabanuka byagaragaye ko ari byinshi ku bantu bafite calcium nkeya. Kubwibyo, muri "Ibyifuzo Byasabwe Kuzuza Kalisiyumu mugihe cyo Gutwita Kurinda Preeclampsia ningaruka zabyo" byashyizwe ahagaragara n’umuryango w’ubuzima ku isi (OMS) mu Gushyingo 2018, birasabwa ko abantu bafite calcium nkeya bagomba kongeramo calcium hamwe na mg 1500 kugeza 2000 mg buri munsi, bagabanijwemo dosiye eshatu zo mu kanwa, ndetse n’amasaha menshi hagati yo gufata fer kugira ngo birinde preeclampsia. Impuguke z’Ubushinwa ku bijyanye no kongerera Kalisiyumu ku bagore batwite, zashyizwe ahagaragara muri Gicurasi 2021, zirasaba ko abagore batwite bafite calcium nkeya yongerera calcium 1000 ~ 1500 mg buri munsi kugeza babyaye.

Kugeza ubu, ibihugu bike n’uturere ni byo byashyize mu bikorwa inyongera ya calcium nini ya calcium mu gihe cyo gutwita, impamvu zirimo ubwinshi bwimiterere ya dosiye ya calcium, bigoye kuyimira, gahunda yubuyobozi igoye (inshuro eshatu kumunsi, kandi igomba gutandukanywa nicyuma), kandi kubahiriza imiti bikagabanuka; Mu turere tumwe na tumwe, kubera amikoro make hamwe nigiciro kinini, calcium ntabwo yoroshye kuyibona, bityo rero birashoboka ko inyongera nini ya calcium yunguka bigira ingaruka. Mu bigeragezo bivura ubushakashatsi bwiyongera kuri calcium nkeya mu gihe cyo gutwita (cyane cyane mg 500 ku munsi), nubwo ugereranije na placebo, ibyago byo kwandura preeclampsia byagabanutse mu itsinda ryongera calcium (RR, 0.38; 95% CI, 0.28 ~ 0.52), ariko ni ngombwa kumenya ko hariho ubushakashatsi bukabije bubogamye [3]. Mu igeragezwa rimwe gusa ry’amavuriro ugereranije n’inyongera ya calcium yuzuye kandi yuzuye ya calcium, ibyago bya preeclampsia byagaragaye ko byagabanutse mu itsinda ryinshi ugereranije n’itsinda rito (RR, 0.42; 95% CI, 0.18 ~ 0.96); Nta tandukaniro ryari mu byago byo kubyara imburagihe (RR, 0.31; 95% CI, 0.09 ~ 1.08)